Data vs Biology: Weight Loss and AI

Par Gabriel Goldberg 27 March 2026 5 min read

Two weeks ago, I wrote in these pages about how I had turned an artificial intelligence into a ruthless nutritional coach . The principle was seductive: reduce weight loss to a simple mathematical equation. Calories in, calories out. Protein count per day. A massive deficit, optimised proteins, and the promise of a rapid, linear physical transformation. A few days later, Eleonore de Richecour , expert nutritionist, published an excellent response on Metis Maven: "AI Counts, Humans Heal" . She rightly reminded us that the machine is blind to physiology, nervous fatigue, and the complexity of living organisms. Today, after several weeks of a "commando protocol" (a deficit sometimes brushing -1,500 kcal per day), I must admit one thing: she was right. But the story does not end there. Here is what really happens when a perfect algorithm takes the controls of an imperfect human body. The Myth of the Straight Line and the Law of Homeostasis On a screen or a spreadsheet, weight loss is a beautiful descending curve. In reality, it is trench warfare against your own evolution. One of the most universal and most frustrating concepts of the human body is called homeostasis: your organism's absolute will to maintain its equilibrium. When you impose an extreme caloric deficit on your body to lose fat (the famous "cut"), your reptilian brain does not think: "Perfect, we are getting lean for summer." It thinks: "Red alert, we are going through a famine." This is where data hits the…